Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618342 | 0.87 | HTT (0.37) | MAPK10MAPK9MAPK8HTTLMNA | |
| SCHEMBL5618494 | 0.87 | MAPK10 (0.62) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL5618225 | 0.86 | ALDH1A1 (0.47) | MAPK10MAPK9MAPK8HTTLMNA | |
| SCHEMBL3574117 | 0.82 | MAPK10 (0.52) | MAPK10MAPK9MAPK8GAAMKNK1 | |
| SCHEMBL5618086 | 0.80 | MAPK10 (0.44) | MAPK10MAPK9MAPK8HTTLMNA | |
| SCHEMBL5618230 | 0.79 | MAPK9 (0.54) | MAPK10MAPK9MAPK8HTTGAA | |
| SCHEMBL5617597 | 0.77 | RAC1 (0.43) | MAPK10MAPK9MAPK8GAAMKNK1 | |
| SCHEMBL5398186 | 0.75 | MAPK8 (0.48) | MAPK10MAPK9MAPK8HTTGAA | |
| SCHEMBL5618317 | 0.75 | ALDH1A1 (0.41) | MAPK10MAPK9MAPK8HTTMKNK2 | |
| SCHEMBL5617848 | 0.74 | MAPK8 (0.49) | MAPK10MAPK9MAPK8GAAMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203134-A1 | Benzimidazole Acetonitriles | PKD1, GPR119, CCNI | MAPK10 4253/4885MAPK9 3702/4885MAPK8 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.