Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.42 |
| ▸ | TUBB | P07437 | 6/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351018 | 0.93 | L3MBTL1 (0.44) | POLBL3MBTL1ABCB1AMY1ATUBB4A | |
| SCHEMBL5620415 | 0.90 | TUBB4A (0.42) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5619314 | 0.84 | FYN (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5619170 | 0.83 | ABCG2 (0.51) | POLBABCB1MAPTKMT2AMEN1 | |
| SCHEMBL6288529 | 0.82 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6288553 | 0.80 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5621436 | 0.80 | FYN (0.48) | POLBMAPTGAAHPGDNPSR1 | |
| SCHEMBL5916485 | 0.80 | ALDH1A1 (0.46) | POLBABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5916391 | 0.80 | EGFR (0.32) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6291396 | 0.79 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202243-B2 | Substituted imidazotriazines | BAYER HEALTHCARE AG (DE) | 2007-04-10 | — | — | US | disclosed |
| US-7202243-B2 | Substituted imidazotriazines | BAYER HEALTHCARE AG (DE) | 2007-04-10 | — | — | US | disclosed |
| US-7202243-B2 | Substituted imidazotriazines | BAYER HEALTHCARE AG (DE) | 2007-04-10 | — | — | US | disclosed |
| US-20060166993-A1 | Substituted imidazotriazines | BAYER HEALTHCARE AG (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1599479-A1 | SUBSTITUTED IMIDAZOTRIAZINES | Bayer HealthCare AG (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004005290-A1 | SUBSTITUTED IMIDAZOTRIAZINES | BAYER HEALTHCARE AG (DE) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166993-A1 | Substituted imidazotriazines | SNCA, PARK7, TPMT | POLB 1909/4885L3MBTL1 2777/4885ABCB1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.