Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5619566 | 0.96 | NOS1 (0.35) | NOS1NOS2NOS3 | |
| SCHEMBL7856571 | 0.96 | NOS1 (0.37) | NOS1NOS2NOS3NISCH | |
| SCHEMBL31369274 | 0.74 | NOS1 (0.41) | NOS1NOS2NOS3 | |
| SCHEMBL3614022 | 0.71 | NOS1 (0.47) | NOS1NOS2NOS3 | |
| SCHEMBL3614020 | 0.71 | NOS1 (0.47) | NOS1NOS2NOS3 | |
| SCHEMBL11190048 | 0.68 | NOS1 (0.36) | NOS1NOS2NOS3 | |
| SCHEMBL25209847 | 0.56 | NOS3 (0.41) | NOS1NOS2NOS3NISCH | |
| SCHEMBL30749698 | 0.55 | NOS1 (0.38) | NOS1NOS2NOS3 | |
| SCHEMBL6396181 | 0.55 | CHRM3 (0.43) | NISCH | |
| SCHEMBL18849280 | 0.53 | ALDH1A1 (0.41) | NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |