Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.56 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.42 |
| ▸ | CBLB | Q13191 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475893 | 0.98 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| Bromide SCHEMBL10937076 | 0.97 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| Hydrochloric Acid SCHEMBL6118177 | 0.95 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| Hydrochloric Acid SCHEMBL17414844 | 0.89 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| SCHEMBL31509638 | 0.89 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| Hydrochloric Acid SCHEMBL3901312 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| SCHEMBL14652902 | 0.87 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| SCHEMBL3764640 | 0.87 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| SCHEMBL2586583 | 0.86 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2KMT2AATMBBOX1 | |
| SCHEMBL15830115 | 0.86 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2KMT2AATMCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094537-A1 | COMPOSITION COMPRISING A PARTICULAR SILICONE, A PARTICULAR SILICONE EMULSION, A PARTICULAR VINYLIC POLYMER AND SURFACTANTS | L'OREAL (FR) | 2024-05-10 | — | — | WO | claimed |
| EP-3490622-B1 | METHODS AND COMPOSITIONS FOR WOUND HEALING | IMBED BIOSCIENCES INC (US) | 2023-09-06 | — | — | EP | claimed |
| CN-116144198-A | Antifogging agent special for transparent polyolefin film | 广西平果市润丰钙新材料科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| WO-2022136095-A1 | COMPOSITION COMPRISING A SILICONE EMULSION, A PARTICULAR (METH)ACRYLAMIDE POLYMER, A CATIONIC POLYSACCHARIDE AND AN ALKYLDIALLYLAMINE OR DIALKYLDIALLYLAMMONIUM POLYMER | L'OREAL (FR) | 2022-06-30 | — | — | WO | claimed |
| CN-109455759-B | Nano hollow titanium dioxide microsphere with low refractive index and high catalytic activity and preparation method thereof | 东莞南玻太阳能玻璃有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-105492971-B | The method of the orientation of block copolymer mesoscopic structure is controlled by random copolymer | 阿科玛法国公司 | 2019-09-10 | — | — | CN | claimed |
| CN-109455759-A | Nano hollow titanium dioxide microsphere with low refractive index and high catalytic activity and preparation method thereof | 东莞南玻太阳能玻璃有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-108603342-A | Method for improving drainage performance of paper pulp slurry in paper product manufacturing process and product thereof | 索伦伊斯技术有限合伙公司 | 2018-09-28 | — | — | CN | claimed |
| CN-105964195-A | Nanometer core-shell silicon dioxide microsphere as well as preparation and application of antireflection composite coating solution | 东莞南玻太阳能玻璃有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105189589-A | Polymers prepared from alkoxylated polyamines | AKZO NOBEL CHEMICALS INT BV | 2015-12-23 | — | — | CN | claimed |
| CN-105188851-A | Shampoo composition and method of making same | PROCTER & GAMBLE | 2015-12-23 | — | — | CN | claimed |
| US-12605326-B2 | Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant | L'OREAL (FR) | 2026-04-21 | — | — | US | disclosed |
| CN-116144198-B | Antifogging agent special for transparent polyolefin film | 广西平果市润丰钙新材料科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2024094537-A1 | COMPOSITION COMPRISING A PARTICULAR SILICONE, A PARTICULAR SILICONE EMULSION, A PARTICULAR VINYLIC POLYMER AND SURFACTANTS | L'OREAL (FR) | 2024-05-10 | — | — | WO | disclosed |
| EP-2723308-B2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMPHOTERIC POLYMER AND AT LEAST ONE PARTICULAR CONDITIONING AGENT | OREAL (FR) | 2023-08-30 | — | — | EP | disclosed |
| EP-1260379-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-1251013-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-0627324-B1 | Ink jet recording medium | MITSUBISHI PAPER MILLS LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5439739-A | Support having ink receiving layer containing crosslinked water soluble polymer with repeating units derived from quaternary ammonium salts, amines, acids and amides; water resistance | MITSUBISHI PAPER MILLS LIMITED (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0627324-A1 | Ink jet recording medium | MITSUBISHI PAPER MILLS, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605326-B2 | Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant | MSH6, KRT18, MMAB | ZDHHC20 2982/4885ZDHHC2 4424/4885KMT2A 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.