Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | CBLB | Q13191 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764640 | 0.98 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL6117271 | 0.96 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL562283 | 0.89 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6118177 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL475893 | 0.87 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2551112 | 0.87 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL10937076 | 0.86 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1875906 | 0.85 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8973398 | 0.84 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28837461 | 0.84 | KMT2A (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188851-A | Shampoo composition and method of making same | PROCTER & GAMBLE | 2015-12-23 | — | — | CN | claimed |
| CN-111050903-B | Chromatographic packing material for separating and/or detecting methylated DNA | 积水医疗株式会社 | 2023-02-28 | — | — | CN | disclosed |
| CN-106062215-B | Method for determining prognosis of renal cell carcinoma | 国立研究开发法人国立癌研究中心 | 2020-09-22 | — | — | CN | disclosed |
| CN-111057752-A | Application of ion exchange chromatography and application of PCR (polymerase chain reaction) primer | 国立研究开发法人国立癌研究中心 | 2020-04-24 | — | — | CN | disclosed |
| CN-111050903-A | Chromatographic packing material for separating and/or detecting methylated DNA | 积水医疗株式会社 | 2020-04-21 | — | — | CN | disclosed |
| US-10550426-B2 | Method for detecting methylated DNA | SEKISUI MEDICAL CO., LTD. (JP) | 2020-02-04 | — | — | US | disclosed |
| CN-109952131-A | Concentrated shampoos containing hydrofluoro-or hydrochlorofluoro-olefins for delivering composition and foam-type property benefits | 宝洁公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109952088-A | Compositions comprising scalp health agents with increased deposition | 宝洁公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109890355-A | Concentrated shampoo foam formulations for providing hair care benefits | 宝洁公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109862943-A | For providing the concentrated type shampoo foam of hair-care beneficial effect | 宝洁公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-104583254-B | Fluorinated copolymer and its manufacture method, water repellent compositionss, article | 旭硝子株式会社 | 2017-03-08 | — | — | CN | disclosed |
| US-20160138097-A1 | METHOD FOR DETECTING METHYLATED DNA | SEKISUI MEDICAL CO., LTD. (JP) | 2016-05-19 | — | — | US | disclosed |
| CN-102459494-B | The treatment process of water-repellent/oil-repellent composition, its manufacture method and article | ASAHI GLASS CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| EP-2966179-A1 | METHOD FOR DETECTING METHYLATED DNA | Sekisui Medical Co., Ltd. (JP) | 2016-01-13 | — | — | EP | disclosed |
| CN-105188851-A | Shampoo composition and method of making same | PROCTER & GAMBLE | 2015-12-23 | — | — | CN | disclosed |
| CN-103492521-B | Water-repellent oil-repellent agent composition, its manufacture method and article | ASAHI GLASS CO.,LTD. (JP) | 2015-08-19 | — | — | CN | disclosed |
| CN-103492520-B | Water-repellent oil-repellent agent composition, its manufacture method and article | ASAHI GLASS CO.,LTD. (JP) | 2015-08-19 | — | — | CN | disclosed |
| CN-104755139-A | Shampoo composition comprising low viscosity silicone polymers | PROCTER & GAMBLE | 2015-07-01 | — | — | CN | disclosed |
| CN-104755138-A | Shampoo composition comprising low viscosity emulsified silicone polymers | PROCTER & GAMBLE | 2015-07-01 | — | — | CN | disclosed |
| CN-104583254-A | Antifouling coating composition | ASAHI GLASS CO LTD | 2015-04-29 | — | — | CN | disclosed |