Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5623997 | 0.89 | AR (0.41) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL5622452 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL5622456 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL5623159 | 0.82 | LCK (0.53) | KDM4EALDH1A1LCKMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5622861 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Trifluoroacetic Acid SCHEMBL5622863 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL5624887 | 0.81 | KMT2A (0.47) | KDM4EALDH1A1HSD17B10HPGDLCK | |
| Ammonia Solution, Strong SCHEMBL6443994 | 0.78 | KDM4C (0.40) | KDM4EALDH1A1HPGDHTTLCK | |
| SCHEMBL14473923 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Trifluoroacetic Acid SCHEMBL5624001 | 0.76 | DPP4 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | INSERM (INSTITUT NATIONAL DE LA SANT'E ET DE LA RECHERCHE MEDICALE (FR) | 2007-07-12 | — | — | US | disclosed |
| EP-1711483-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACID SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005075448-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACIDS SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | CRYAA, BCAT2, BCAT1 | KDM4E 3515/4885ALDH1A1 874/4885HSD17B10 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.