Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 14/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116370 | 0.87 | CXCR3 (0.56) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL5127203 | 0.77 | PSEN1 (0.50) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL5127197 | 0.77 | PSEN1 (0.50) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL5117436 | 0.75 | TAS2R14 (0.74) | CXCR3TAS2R14MEN1KMT2A | |
| SCHEMBL5115952 | 0.74 | TAS2R14 (0.60) | CXCR3TAS2R14MEN1KMT2A | |
| SCHEMBL1170300 | 0.74 | CXCR3 (0.85) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL1287435 | 0.72 | MEN1 (0.66) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL1287403 | 0.72 | MEN1 (0.62) | CXCR3TAS2R14MEN1KMT2ATP53 | |
| SCHEMBL6526322 | 0.71 | PSEN1 (0.46) | CXCR3TMEM97SIGMAR1 | |
| SCHEMBL27268243 | 0.71 | CA9 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163942-B2 | Sulfonamide compounds for the treatment of neurodegenerative disorders | PFIZER INC. (US) | 2007-01-16 | — | — | US | disclosed |