Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.81 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.81 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.81 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.81 |
| ▸ | RAF1 | P04049 | 6/20 | 0.81 |
| ▸ | BRAF | P15056 | 5/20 | 0.81 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | GCGR | P47871 | 2/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068914 | 0.90 | PTPN1 (0.94) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL12561702 | 0.88 | PTPN1 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6469184 | 0.84 | MAPK14 (0.90) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| Phloroglucinol SCHEMBL28606657 | 0.83 | PTPN1 (0.72) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL18292682 | 0.80 | PTPN1 (0.70) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL252964 | 0.80 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9619859 | 0.80 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5307418 | 0.80 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL15401173 | 0.80 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL18292488 | 0.80 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112061-A1 | Heat- or singlet oxygen-generating agents and cancer treatment compositions comprising organic peroxide or chemiluminescent compound | MANAC INC. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112061-A1 | Heat- or singlet oxygen-generating agents and cancer treatment compositions comprising organic peroxide or chemiluminescent compound | HSPE1, MCL1, HMOX1 | MAPK14 758/4885MAPK13 1707/4885MAPK12 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.