Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27656883 | 0.87 | MAP3K11 (0.38) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL1997957 | 0.79 | CYP11B2 (0.44) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL26683830 | 0.77 | CRBN (0.47) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL9088237 | 0.75 | PDE3B (0.66) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL8340084 | 0.72 | CYP1A2 (0.46) | CYP11B2ARCYP1A2CYP11B1MAPT | |
| SCHEMBL25337945 | 0.70 | CRBN (0.54) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL6606774 | 0.69 | CYP11B2 (0.39) | CYP11B2DRD2DRD4MAP3K11 | |
| SCHEMBL8340917 | 0.69 | NOTUM (0.41) | CYP11B2CRBNDRD2HTR1AAR | |
| SCHEMBL31599425 | 0.69 | DRD2 (0.45) | CYP11B2CRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL18011097 | 0.69 | ADRB2 (0.54) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179122-A1 | Beta-Aminoacid-Derivatives As Factor Xa Inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-02 | — | — | US | disclosed |
| EP-1723164-A1 | BETA-AMINOACID-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005095440-A1 | BETA-AMINOACID-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-10-13 | — | — | WO | disclosed |
| EP-1571154-A1 | Beta-aminoacid-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179122-A1 | Beta-Aminoacid-Derivatives As Factor Xa Inhibitors | F12, F11, F5 | CYP11B2 3430/4885CRBN 3732/4885PDE3B 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.