Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56740 | 0.92 | HDAC1 (0.50) | HDAC1HDAC2TGM2CTSLELANE | |
| SCHEMBL56584 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2CTSLELANEPRTN3 | |
| SCHEMBL56832 | 0.83 | HDAC1 (0.53) | HDAC1HDAC2TGM2CTSLP2RX7 | |
| SCHEMBL56757 | 0.82 | HDAC1 (0.51) | HDAC1HDAC2TGM2CTSL | |
| SCHEMBL8433892 | 0.81 | CTSL (0.62) | HDAC1HDAC2TGM2CTSLP2RX7 | |
| SCHEMBL8433969 | 0.81 | CTSL (0.62) | HDAC1HDAC2TGM2CTSLP2RX7 | |
| SCHEMBL8436808 | 0.81 | CTSL (0.62) | HDAC1HDAC2TGM2CTSLP2RX7 | |
| SCHEMBL8435352 | 0.81 | HDAC1 (0.63) | HDAC1HDAC2TGM2CTSL | |
| SCHEMBL8435348 | 0.81 | HDAC1 (0.63) | HDAC1HDAC2TGM2CTSL | |
| SCHEMBL9798018 | 0.80 | HDAC1 (0.57) | HDAC1HDAC2TGM2CTSLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | HDAC1 3626/4885HDAC2 3661/4885TGM2 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.