Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 6/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56268 | 0.92 | HDAC1 (0.54) | HDAC1HDAC2CTSLTGM2P2RX7 | |
| SCHEMBL56584 | 0.90 | HDAC1 (0.52) | HDAC1HDAC2CTSLKYNUELANE | |
| SCHEMBL57116 | 0.88 | ATM (0.51) | CTSLKYNUELANEPRTN3 | |
| SCHEMBL56409 | 0.88 | KYNU (0.50) | CTSLKYNUTGM2ELANEPRTN3 | |
| SCHEMBL56467 | 0.87 | TP53 (0.55) | CTSLKYNUELANEPRTN3 | |
| SCHEMBL57136 | 0.86 | KYNU (0.48) | CTSLKYNUELANEPRTN3 | |
| SCHEMBL56936 | 0.85 | CASP1 (0.48) | CTSLKYNUELANEPRTN3 | |
| SCHEMBL56615 | 0.84 | CTSS (0.48) | CTSLKYNUP2RX7ELANEPRTN3 | |
| SCHEMBL56921 | 0.84 | KYNU (0.47) | CTSLKYNUTGM2P2RX7ELANE | |
| SCHEMBL21174074 | 0.84 | KYNU (0.59) | CTSLKYNUELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137446-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2008-11-13 | — | — | WO | claimed |
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
| WO-2008137446-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | HDAC1 3626/4885HDAC2 3661/4885CTSL 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.