SCHEMBL5627436

SCHEMBL5627436

CC(C)(C)c1cc(CCC(=O)O)cc(-n2nc3ccc(S(=O)(=O)c4ccccc4)cc3n2)c1O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.38
MAOA P21397 2/20 0.38
CYP26B1 Q9NR63 1/20 0.37
GAA P10253 4/20 0.37
ACHE P22303 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
AGTR1 P30556 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CNR2 P34972 1/20 0.35
NAMPT P43490 1/20 0.34
SFRP1 Q8N474 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5834851 0.93 MAOB (0.37) MAOBMAOAGAAACHEKMT2A
SCHEMBL7787071 0.93 MAOB (0.37) MAOBMAOAGAAACHEKMT2A
SCHEMBL4822523 0.91 MAOB (0.40) MAOBMAOAGAAACHEKMT2A
SCHEMBL5834070 0.89 CNR2 (0.35) MAOBMAOAGAAACHEKMT2A
SCHEMBL100766 0.87 MAOB (0.45) MAOBMAOAGAAACHEKMT2A
SCHEMBL29768287 0.87 MAOB (0.45) MAOBMAOAGAAACHEKMT2A
SCHEMBL8053946 0.85 MAOB (0.37) MAOBMAOAGAAACHEKMT2A
SCHEMBL5834156 0.85 CNR2 (0.37) MAOBMAOAALDH1A1CNR2
SCHEMBL21586972 0.84 POLB (0.37) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL5347622 0.84 FKBP1A (0.33) MAOBMAOAGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252147-B1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-08-24 EP claimed
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 US claimed
JP-2005517787-A 2005-06-16 JP claimed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 EP claimed
WO-2003070819-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-08-28 WO claimed
US-6508847-B2 Discoloration inhibition; stability CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 US claimed
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2001-09-20 US claimed
EP-0572554-B1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-05-10 EP claimed
US-5977219-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 US claimed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP claimed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
US-7157586-B2 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORPORATION (US) 2007-01-02 US disclosed
EP-1252147-B1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-08-24 EP disclosed
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 US disclosed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 EP disclosed
WO-2001056998-A1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed
EP-0572554-B1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-05-10 EP disclosed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US disclosed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP disclosed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith FAAH, DBF4, TPH1 MAOB 329/4885MAOA 150/4885CYP26B1 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.