Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245979 | 0.89 | ACHE (0.36) | ACHE | |
| SCHEMBL5627064 | 0.85 | DRD2 (0.32) | — | |
| SCHEMBL428104 | 0.78 | OPRD1 (0.41) | ACHE | |
| SCHEMBL5626006 | 0.77 | CHRM2 (0.36) | — | |
| SCHEMBL448065 | 0.77 | OPRD1 (0.40) | — | |
| SCHEMBL5626839 | 0.76 | NOTUM (0.35) | — | |
| SCHEMBL1451614 | 0.75 | NOTUM (0.36) | — | |
| SCHEMBL4102749 | 0.73 | ACHE (0.47) | CYP1A2CYP2D6ACHE | |
| SCHEMBL1450529 | 0.73 | KDM4E (0.36) | CYP1A2CYP2D6 | |
| SCHEMBL1450311 | 0.73 | SIGMAR1 (0.33) | CYP1A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307088-B2 | Substituted anthranilic amide derivatives and methods of use | AMGEN INC. (US) | 2007-12-11 | — | — | US | disclosed |
| EP-1519921-A2 | SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE | Amgen Inc. (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005279-A2 | SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2004-01-15 | — | — | WO | disclosed |