Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605720 | 0.89 | ALDH1A1 (0.35) | CNR2 | |
| SCHEMBL1386359 | 0.75 | JAK2 (0.36) | CNR2 | |
| SCHEMBL1385639 | 0.69 | ADRA2A (0.39) | CNR2 | |
| SCHEMBL1607462 | 0.69 | ADRA2A (0.39) | CNR2 | |
| SCHEMBL1605818 | 0.67 | LMNA (0.35) | CNR1CNR2 | |
| SCHEMBL1605753 | 0.64 | CNR1 (0.30) | CNR1CNR2 | |
| SCHEMBL1605155 | 0.57 | RAB9A (0.40) | — | |
| SCHEMBL1383500 | 0.57 | SMN1; SMN2 (0.46) | CNR1CNR2 | |
| SCHEMBL1605127 | 0.56 | POLB (0.32) | — | |
| SCHEMBL1605454 | 0.55 | ADRA2A (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253196-B2 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 | AMGEN, INC. (US) | 2007-08-07 | — | — | US | disclosed |