Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930107 | 0.82 | S1PR4 (0.35) | — | |
| SCHEMBL13343549 | 0.80 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL2125060 | 0.79 | NOS3 (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL929424 | 0.79 | KDM4E (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL9550990 | 0.76 | KDM4E (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL930346 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL928988 | 0.73 | HTR2A (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL5632552 | 0.72 | NCF1 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL4546535 | 0.72 | HTR6 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL2688403 | 0.72 | CD274 (0.34) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208603-B2 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2007-04-24 | — | — | US | disclosed |
| EP-1358179-B1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PF MEDICAMENT (FR) | 2006-05-10 | — | — | EP | disclosed |
| US-20040116705-A1 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2004-06-17 | — | — | US | disclosed |
| EP-1358179-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002064585-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2002-08-22 | — | — | WO | disclosed |