Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379121 | 0.85 | ACACB (0.43) | ACACBHRH3NAMPTGPR6 | |
| SCHEMBL22678144 | 0.83 | FFAR1 (0.47) | ACACBHRH3NAMPTIDO1TDO2 | |
| SCHEMBL9760149 | 0.83 | IDO1 (0.45) | ACACBHRH3NAMPTIDO1TDO2 | |
| SCHEMBL5633968 | 0.83 | NAMPT (0.43) | ACACBHRH3NAMPT | |
| SCHEMBL5632543 | 0.82 | CHKA (0.46) | ACACBHRH3GPR6CHKAKDM1A | |
| SCHEMBL5632393 | 0.82 | NAMPT (0.56) | ACACBHRH3NAMPT | |
| Hydrochloric Acid SCHEMBL7954922 | 0.81 | CHKA (0.44) | ACACBHRH3GPR6CHKAKDM1A | |
| SCHEMBL7112229 | 0.79 | F10 (0.49) | ACACBHRH3NAMPT | |
| SCHEMBL3440129 | 0.78 | CHKA (0.55) | HRH3CHKA | |
| SCHEMBL5632556 | 0.78 | ALDH1A1 (0.56) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | disclosed |
| EP-0880502-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ASTRAZENECA AB (SE) | 2004-09-01 | — | — | EP | disclosed |
| US-20030207882-A1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207882-A1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | F2, SERPINC1, F11 | ACACB 2543/4885HRH3 279/4885NAMPT 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.