Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264618 | 0.97 | ALDH1A1 (0.46) | ALDH1A1PKMCD274PDCD1KDM4E | |
| SCHEMBL10203790 | 0.86 | CD274 (0.41) | ALDH1A1PKMCD274PDCD1KDM4E | |
| SCHEMBL10010968 | 0.85 | FFAR1 (0.48) | CD274PDCD1FFAR1 | |
| SCHEMBL562357 | 0.83 | RECQL (0.52) | CD274 | |
| SCHEMBL10264739 | 0.83 | ALDH1A1 (0.43) | ALDH1A1PKMCD274PDCD1KDM4E | |
| SCHEMBL10203716 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PKMCD274PDCD1KDM4E | |
| SCHEMBL10264348 | 0.82 | RECQL (0.47) | ALDH1A1PKMCD274PDCD1FFAR1 | |
| SCHEMBL562625 | 0.81 | FFAR1 (0.41) | ALDH1A1PKMKDM4EMAPTMCL1 | |
| SCHEMBL13084411 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PKMKDM4EMAPTMCL1 | |
| SCHEMBL10203757 | 0.79 | CA1 (0.47) | CD274PDCD1MCL1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423176-A1 | CARBOXYLIC ACID COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120035196-A1 | CARBOXYLIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035196-A1 | CARBOXYLIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035196-A1 | CARBOXYLIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-09 | — | — | US | disclosed |
| WO-2010123016-A1 | CARBOXYLIC ACID COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035196-A1 | CARBOXYLIC ACID COMPOUND | GPR119, GPR65, GPR55 | ALDH1A1 1534/4885PKM 2941/4885CD274 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.