Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12156482 | 0.94 | KCNH2 (0.60) | KCNH2MAPTMAOBCHRM2HTR1A | |
| SCHEMBL22403770 | 0.90 | KCNH2 (0.66) | KCNH2MAPTMAOBCHRM2HTR1A | |
| SCHEMBL9670343 | 0.90 | KCNH2 (0.65) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10530872 | 0.90 | KCNH2 (0.71) | KCNH2MAPTCHRM2HTR1AADRA2A | |
| SCHEMBL9670241 | 0.88 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670944 | 0.88 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671701 | 0.88 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671564 | 0.88 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL3161700 | 0.86 | GFER (0.54) | KCNH2MAPTMAOBCHRM2HTR1A | |
| SCHEMBL10529931 | 0.84 | MAPT (0.64) | KCNH2MAPTMAOBCHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | disclosed |
| EP-1844048-B1 | PYRAZOLOPYRIMIDINES AS CELL CYCLE KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-26 | — | — | EP | disclosed |
| US-7288566-B2 | N-hydroxyformamidine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-30 | — | — | US | disclosed |
| US-20060004078-A1 | N-hydroxyformamidine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004078-A1 | N-hydroxyformamidine derivatives | FLT4, FLT1, PGF | KCNH2 3676/4885MAPT 4857/4885MAOB 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.