Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633167 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRALOX15LMNAKMT2A | |
| SCHEMBL7114329 | 0.90 | F10 (0.51) | ALDH1A1TSHRALOX15LMNANAMPT | |
| SCHEMBL7114331 | 0.90 | F10 (0.51) | ALDH1A1TSHRALOX15LMNANAMPT | |
| SCHEMBL5632002 | 0.89 | ALDH1A1 (0.49) | ALDH1A1TSHRALOX15LMNAKMT2A | |
| SCHEMBL5632000 | 0.89 | ALDH1A1 (0.49) | ALDH1A1TSHRALOX15LMNAKMT2A | |
| SCHEMBL5633362 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15LMNAKMT2A | |
| SCHEMBL5633359 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15LMNAKMT2A | |
| SCHEMBL5633179 | 0.81 | F10 (0.48) | ALDH1A1TSHRALOX15F10 | |
| SCHEMBL5633181 | 0.81 | F10 (0.48) | ALDH1A1TSHRALOX15F10 | |
| SCHEMBL9760149 | 0.80 | IDO1 (0.45) | TSHRNAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | claimed |
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | disclosed |
| EP-0880502-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ASTRAZENECA AB (SE) | 2004-09-01 | — | — | EP | disclosed |