Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633362 | 1.00 | ALDH1A1 (0.54) | ALDH1A1ALOX15TSHRLMNAF10 | |
| SCHEMBL7113715 | 0.91 | F10 (0.55) | ALDH1A1ALOX15TSHRF10HRH2 | |
| SCHEMBL7113722 | 0.91 | F10 (0.55) | ALDH1A1ALOX15TSHRF10HRH2 | |
| SCHEMBL5633166 | 0.85 | ALDH1A1 (0.57) | ALDH1A1ALOX15TSHRLMNAF10 | |
| SCHEMBL5633167 | 0.85 | ALDH1A1 (0.57) | ALDH1A1ALOX15TSHRLMNAF10 | |
| SCHEMBL9759900 | 0.81 | ADRB1 (0.52) | F10HRH2HRH1HRH3ADRB1 | |
| SCHEMBL5632390 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAF10KMT2AHRH2 | |
| SCHEMBL9761013 | 0.79 | F10 (0.47) | F10HRH2HRH1HRH3ADRB1 | |
| SCHEMBL5631650 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAF10KMT2AHRH1 | |
| SCHEMBL5632002 | 0.77 | ALDH1A1 (0.49) | ALDH1A1ALOX15TSHRLMNAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | claimed |
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | disclosed |