Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 12/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632000 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ALOX15TSHRF10GHSR | |
| SCHEMBL5633181 | 0.92 | F10 (0.48) | ALDH1A1ALOX15TSHRF10F2 | |
| SCHEMBL5633179 | 0.92 | F10 (0.48) | ALDH1A1ALOX15TSHRF10F2 | |
| SCHEMBL5633167 | 0.89 | ALDH1A1 (0.57) | ALDH1A1ALOX15TSHRF10GHSR | |
| SCHEMBL5633166 | 0.89 | ALDH1A1 (0.57) | ALDH1A1ALOX15TSHRF10GHSR | |
| SCHEMBL7114331 | 0.80 | F10 (0.51) | ALDH1A1ALOX15TSHRF10LMNA | |
| SCHEMBL7114329 | 0.80 | F10 (0.51) | ALDH1A1ALOX15TSHRF10LMNA | |
| SCHEMBL5632729 | 0.78 | F2 (0.55) | ALDH1A1F10GHSRPKMKMT2A | |
| SCHEMBL6580787 | 0.77 | GHSR (0.48) | F10GHSRF2 | |
| SCHEMBL5633359 | 0.77 | ALDH1A1 (0.54) | ALDH1A1ALOX15TSHRF10GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | claimed |
| US-7173025-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2007-02-06 | — | — | US | disclosed |
| EP-0880502-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ASTRAZENECA AB (SE) | 2004-09-01 | — | — | EP | disclosed |