SCHEMBL5633600

SCHEMBL5633600

C[Si](C)(C)OC(C#N)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 8/20 0.41
KDM4E B2RXH2 6/20 0.41
HTT P42858 3/20 0.41
HSD17B10 Q99714 3/20 0.41
ALOX15 P16050 2/20 0.41
MAPK1 P28482 2/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
LMNA P02545 5/20 0.41
TSHR P16473 2/20 0.41
NSD2 O96028 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7089384 0.74 ALDH1A1 (0.39) ALDH1A1KMT2AMAPTKDM4EHTT
SCHEMBL4671383 0.73 ALDH1A1 (0.40) ALDH1A1MAPTHTTMAPK1LMNA
SCHEMBL16094149 0.73 CYP19A1 (0.41) ALDH1A1HTTTSHRCYP3A4CYP2C19
SCHEMBL6718841 0.73 LMNA (0.39) ALDH1A1KMT2AHTTUSP2SMN1; SMN2
SCHEMBL7575011 0.73 LMNA (0.39) ALDH1A1KMT2AHTTUSP2SMN1; SMN2
SCHEMBL2610138 0.72 TRPA1 (0.42) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL4876009 0.71 LMNA (0.44) MEN1KMT2AMAPTHTTALOX15
SCHEMBL2387456 0.71 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL5317124 0.71 ALDH1A1 (0.47) ALDH1A1KMT2AMAPTKDM4EHTT
SCHEMBL19717446 0.71 CYP3A4 (0.36) GAACYP17A1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100430385-C Compound for improving storage stability of photoinitiator and application thereof CIBA SC HOLDING AG (CH) 2008-11-05 CN disclosed
US-7291654-B2 Storage stability of photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-06 US disclosed
EP-1556365-B1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-08-30 EP disclosed
US-20060100298-A1 Storage stability of photoinitiators IGM GROUP B.V. (NL) 2006-05-11 US disclosed
CN-1708488-A Improvement of storage stability of photoinitiators CIBA SC HOLDING AG (CH) 2005-12-14 CN disclosed
EP-1556365-A1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS Ciba SC Holding AG (CH) 2005-07-27 EP disclosed
WO-2004037799-A1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-05-06 WO disclosed