Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789913 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL7932437 | 0.86 | ALDH1A1 (0.33) | ALDH1A1GAALMNAHTT | |
| SCHEMBL9297323 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL5525306 | 0.83 | ALDH1A3 (0.37) | ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL12412508 | 0.82 | ALDH1A1 (0.39) | ALDH1A1GAALMNAHTTNPC1 | |
| SCHEMBL6613625 | 0.82 | CA1 (0.40) | ALDH1A1GAAHTTCA1CA2 | |
| SCHEMBL7089384 | 0.81 | ALDH1A1 (0.39) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL7452976 | 0.81 | LTA4H (0.40) | ALDH1A1GAASMN1; SMN2TSHRTDP1 | |
| SCHEMBL14763050 | 0.80 | PDE2A (0.41) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2610137 | 0.80 | L3MBTL1 (0.42) | ALDH1A1HTTCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077141-A1 | METHOD FOR PRODUCING SUBSTITUTED PHENYLACETYL CARBINOLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-5329023-A | Method of preparing optically active alcohols which consist substantially or entirely of one enantiomer | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-07-12 | — | — | US | disclosed |