SCHEMBL5633848

SCHEMBL5633848

Cc1ccc(CC(=O)c2ccc(N3CCOCC3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.60
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
TP53 P04637 1/20 0.59
PKM P14618 1/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 3/20 0.55
AKR1C3 P42330 1/20 0.55
GAA P10253 2/20 0.55
MAPT P10636 6/20 0.52
ALDH1A1 P00352 5/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
KDM4E B2RXH2 1/20 0.52
FAAH O00519 1/20 0.51
MGLL Q99685 1/20 0.51
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2321900 0.85 SMN1; SMN2 (0.60) GSK3BNPC1RAB9AL3MBTL1MAPT
SCHEMBL50144 0.85 SMN1; SMN2 (0.64) GSK3BNPC1RAB9AL3MBTL1MAPT
SCHEMBL15822437 0.84 GSK3B (0.55) GSK3BNPC1RAB9AL3MBTL1MAPT
SCHEMBL8522837 0.83 SMN1; SMN2 (0.57) GSK3BNPC1RAB9ATP53MAPK1
SCHEMBL15709155 0.83 THRA (0.57) GSK3BNPC1RAB9ATP53PKM
SCHEMBL5218244 0.79 NPC1 (0.81) GSK3BNPC1RAB9AL3MBTL1MAPT
SCHEMBL50003 0.79 GSK3B (0.71) GSK3BNPC1RAB9ATP53PKM
SCHEMBL11194026 0.79 MAPT (0.56) GSK3BNPC1RAB9AL3MBTL1GAA
SCHEMBL15752632 0.79 SMN1; SMN2 (0.55) GSK3BNPC1RAB9AL3MBTL1AKR1C3
SCHEMBL82183 0.78 MAPT (0.67) NPC1RAB9ATP53PKMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017095829-A2 PERMANENT DIELECTRIC COMPOSITIONS CONTAINING PHOTOACID GENERATOR AND BASE PROMERUS, LLC (US) 2017-06-08 WO disclosed
WO-2016133795-A1 PHOTOIMAGEABLE POLYOLEFIN COMPOSITIONS CONTAINING PHOTOBASE GENERATORS PROMERUS, LLC (US) 2016-08-25 WO disclosed
US-7291654-B2 Storage stability of photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-06 US disclosed
EP-1556365-B1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-08-30 EP disclosed
US-20060100298-A1 Storage stability of photoinitiators IGM GROUP B.V. (NL) 2006-05-11 US disclosed
EP-1556365-A1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS Ciba SC Holding AG (CH) 2005-07-27 EP disclosed
WO-2004037799-A1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-05-06 WO disclosed