SCHEMBL50144

SCHEMBL50144

O=C(Cc1ccccc1)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.64
GSK3B P49841 1/20 0.63
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAOB P27338 1/20 0.55
MAPT P10636 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
ALDH1A1 P00352 4/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C19 P33261 1/20 0.52
LMNA P02545 1/20 0.51
SRD5A2 P31213 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KDM4E B2RXH2 1/20 0.51
PIK3CD O00329 1/20 0.50
PIK3CA P42336 1/20 0.50
PIK3CB P42338 1/20 0.50
PIK3CG P48736 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2321900 0.94 SMN1; SMN2 (0.60) SMN1; SMN2GSK3BMEN1KMT2AMAOB
SCHEMBL8522837 0.92 SMN1; SMN2 (0.57) SMN1; SMN2GSK3BMEN1KMT2AMAOB
SCHEMBL15822437 0.89 GSK3B (0.55) SMN1; SMN2GSK3BMEN1KMT2AMAOB
SCHEMBL3495303 0.86 KMO (0.68) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL5633848 0.85 GSK3B (0.60) SMN1; SMN2GSK3BMEN1KMT2AMAPT
SCHEMBL25803089 0.84 GSK3B (0.67) SMN1; SMN2GSK3BMEN1KMT2AMAOB
SCHEMBL15548441 0.84 SMN1; SMN2 (0.48) SMN1; SMN2GSK3BMEN1KMT2AMAOB
SCHEMBL14817804 0.84 NPC1 (0.65) SMN1; SMN2MEN1KMT2AMAPTL3MBTL1
SCHEMBL12319792 0.81 MEN1 (0.67) MEN1KMT2ANPC1RAB9A
SCHEMBL3318066 0.81 USP2 (0.60) SMN1; SMN2GSK3BMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
US-20110123721-A1 ENZYMATIC SYNTHESIS OF POLYOL ACRYLATES BASF AKTIENGESELLSCHAFT (DE) 2011-05-26 US claimed
US-12559631-B2 Thermally curable two-component coating compounds BASF SE (DE) 2026-02-24 US disclosed
US-20250368830-A1 METHOD FOR TRANSFERRING AN EMBOSSED STRUCTURE TO THE SURFACE OF A COATING, AND COMPOSITE EMPLOYABLE AS EMBOSSING MOLD BASF COATINGS GMBH (DE) 2025-12-04 US disclosed
EP-3094493-B2 LAYERED BUILDING BOARD FOR INSIDE AND OUTSIDE KRONOPLUS TECHNICAL AG (CH) 2025-09-03 EP disclosed
US-12386253-B2 Method for transferring an embossed structure to the surface of a coating, and composite employable as embossing mold BASF COATINGS GMBH (DE) 2025-08-12 US disclosed
US-20250215122-A1 CURABLE COMPOSITION FOR 3D PRINTING PROCESS AND 3D-PRINTED OBJECT FORMED THEREFROM AND 3D PRINTING PROCESS USING THE SAME BASF SE (DE) 2025-07-03 US disclosed
US-20250178271-A1 METHOD FOR TRANSFERRING AN EMBOSSED STRUCTURE TO THE SURFACE OF A COATING AND COMPOUND STRUCTURE CONTAINING SAID COATING BASF COATINGS GMBH (DE) 2025-06-05 US disclosed
EP-3976344-B1 METHOD FOR APPLYING EMBOSSED STRUCTURES TO COATING MEDIA WHILE PRE-TREATING THE EMBOSSING TOOL USED THEREFOR BASF COATINGS GMBH (DE) 2025-04-30 EP disclosed
EP-0897558-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR RAPID PROTOTYPING AND A PROCESS FOR THE MANUFACTURE OF 3-DIMENSIONAL OBJECTS DSM N.V. (NL) 1999-02-24 EP disclosed
WO-1998010003-A1 AQUEOUS DEVELOPABLE PHOTOSENSITIVE POLYURETHANE-METHACRYLATE POLYFIBRON TECHNOLOGIES, INC. (US) 1998-03-12 WO disclosed
WO-1997042549-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR RAPID PROTOTYPING AND A PROCESS FOR THE MANUFACTURE OF 3-DIMENSIONAL OBJECTS DSM N.V. (NL) 1997-11-13 WO disclosed
US-5523443-A PROTECTIVE COATINGS CASCHEM, INC. (US) 1996-06-04 US disclosed
US-5426132-A Alkoxysilyl-urethane acrylate with two curing mechanisms, one activated by exposure to ultraviolet radiation, second by exposure to moisture CASCHEM, INC. (US) 1995-06-20 US disclosed
US-5312943-A Protective coatings CASCHEM, INC. (US) 1994-05-17 US disclosed
US-4222835-A VINYL MONOMER, PHOTOINITIATOR, THERMAL INITIATOR WESTINGHOUSE ELECTRIC CORP. (US) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559631-B2 Thermally curable two-component coating compounds ESD, MGMT, MTHFD2 SMN1; SMN2 1826/4885GSK3B 2227/4885MEN1 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.