SCHEMBL2321900

SCHEMBL2321900

O=C(Cc1ccc(N2CCOCC2)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
GSK3B P49841 1/20 0.59
MAPT P10636 7/20 0.55
KMT2A Q03164 5/20 0.55
ALDH1A1 P00352 5/20 0.55
MEN1 O00255 3/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
KMO O15229 1/20 0.54
PIK3CD O00329 1/20 0.53
PIK3CA P42336 1/20 0.53
PIK3CB P42338 1/20 0.53
PIK3CG P48736 1/20 0.53
PRKDC P78527 1/20 0.53
LMNA P02545 1/20 0.51
MAOB P27338 1/20 0.51
HSD17B10 Q99714 1/20 0.50
PLOD2 O00469 1/20 0.50
PLOD3 O60568 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8522837 0.94 SMN1; SMN2 (0.57) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL50144 0.94 SMN1; SMN2 (0.64) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL15822437 0.92 GSK3B (0.55) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL3495303 0.86 KMO (0.68) SMN1; SMN2MAPTKMT2AALDH1A1MEN1
SCHEMBL5633848 0.85 GSK3B (0.60) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
Hydrochloric Acid SCHEMBL27324610 0.85 MAPT (0.59) SMN1; SMN2MAPTKMT2AALDH1A1MEN1
SCHEMBL25803089 0.84 GSK3B (0.67) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL2649726 0.82 ITGB3 (0.60) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL50238 0.79 SMN1; SMN2 (0.74) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1
SCHEMBL14982132 0.79 ALDH1A1 (0.61) SMN1; SMN2GSK3BMAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227902-B Liquid photopolymer resin composition for flexographic printing 麦克德米德图像方案股份有限公司 2024-09-27 CN disclosed
EP-3471961-B1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-09-20 EP disclosed
EP-4185468-A1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE Macdermid Graphics Solutions, LLC (US) 2023-05-31 EP disclosed
EP-3610327-B1 METHOD OF IMPROVING LIGHT STABILITY OF FLEXOGRAPHIC PRINTING PLATES FEATURING FLAT TOP DOTS MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-03-22 EP disclosed
US-11602947-B2 Method of making a flexographic printing plate MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-03-14 US disclosed
WO-2022020837-A1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE MACDERMID GRAPHICS SOLUTIONS, LLC (US) 2022-01-27 WO disclosed
US-20220024239-A1 Method of Making a Flexographic Printing Plate MACDERMID GRAPHICS SOLUTIONS LLC 2022-01-27 US disclosed
EP-3906441-A1 LIQUID PHOTOPOLYMER RESIN COMPOSITIONS FOR FLEXOGRAPHIC PRINTING Macdermid Graphics Solutions, LLC (US) 2021-11-10 EP disclosed
EP-3686671-B1 METHOD OF IMPROVING SURFACE CURE IN DIGITAL FLEXOGRAPHIC PRINTING PLATES MACDERMID GRAPHICS SOLUTIONS LLC (US) 2021-09-29 EP disclosed
EP-3683625-B1 METHOD OF IMPROVING SURFACE CURE IN DIGITAL FLEXOGRAPHIC PRINTING PLATES MACDERMID GRAPHICS SOLUTIONS LLC (US) 2021-09-29 EP disclosed
US-4002798-A POLYTHIOETHER ADHESIVE DERIVED FROM HYDANTOIN GLYCOL W. R. GRACE & CO. (US) 1977-01-11 US disclosed
US-3996257-A Polythiocarbamate monomers W. R. GRACE & CO. (US) 1976-12-07 US disclosed
US-3993549-A IMAGING DEVICE W. R. GRACE & CO. (US) 1976-11-23 US disclosed
US-3984297-A PHOTOCURING, CROSSLINKING W. R. GRACE & CO. (US) 1976-10-05 US disclosed
US-3984606-A Curable polyene-polythiol hydantoin coating compositions W. R. GRACE & CO. (US) 1976-10-05 US disclosed
US-3976553-A Curable polyene-polythiol compounds and methods for preparation and curing W. R. GRACE & CO. (US) 1976-08-24 US disclosed
US-3966794-A Curable polyene-polythiol compounds W. R. GRACE & CO. (US) 1976-06-29 US disclosed
US-3950569-A Method for preparing coatings with solid curable compositions containing styrene-allyl alcohol copolymer based polythiols W. R. GRACE & CO. (US) 1976-04-13 US disclosed
US-3945982-A FROM HYDANTOIN GLYCOLS, MOLDING MATERIALS W. R. GRACE & CO. (US) 1976-03-23 US disclosed
US-3936530-A Method for preparing coatings using curable solid styrene-allyl alcohol copolymer based polyene and polythiol compositions W. R. GRACE & CO. (US) 1976-02-03 US disclosed