Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.45 |
| ▸ | TUBB | P07437 | 4/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634381 | 0.88 | TUBB4A (0.52) | HTTLMNATSHRSMN1; SMN2TUBB4A | |
| SCHEMBL6154577 | 0.85 | ALDH1A1 (0.46) | HTTLMNATSHRMAPTALDH1A1 | |
| SCHEMBL5634437 | 0.85 | LMNA (0.47) | HTTLMNATSHRMAPTSMN1; SMN2 | |
| SCHEMBL3610721 | 0.85 | TUBB4A (0.41) | LMNATSHRSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL14514087 | 0.84 | SMN1; SMN2 (0.49) | LMNAMAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5634909 | 0.83 | CNR1 (0.43) | LMNATSHRTUBB4ATUBBTUBA3C | |
| SCHEMBL5633890 | 0.81 | OGA (0.44) | HTTLMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL5633750 | 0.81 | LMNA (0.47) | HTTLMNATSHRMAPTALDH1A1 | |
| SCHEMBL3527660 | 0.81 | LMNA (0.47) | HTTLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5634098 | 0.81 | TUBB4A (0.44) | HTTLMNATSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |