Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514085 | 0.88 | GPR119 (0.48) | CNR1F2RTMEM97 | |
| SCHEMBL5634437 | 0.86 | LMNA (0.47) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL6154577 | 0.86 | ALDH1A1 (0.46) | LMNATSHRMAPK1PPARGPPARA | |
| SCHEMBL5634381 | 0.83 | TUBB4A (0.52) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL5634878 | 0.83 | HTT (0.47) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL5634668 | 0.81 | LMNA (0.50) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL5634552 | 0.80 | LMNA (0.49) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL3610721 | 0.80 | TUBB4A (0.41) | LMNAALOX15TSHRMAPK1PPARG | |
| SCHEMBL5633750 | 0.78 | LMNA (0.47) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL5633890 | 0.76 | OGA (0.44) | CNR1LMNAMAPK1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |