Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 7/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633718 | 0.82 | CACNA2D1 (0.47) | CACNA2D1CACNB1CACNA1ACACNA1CALDH1A1 | |
| SCHEMBL5633709 | 0.74 | CYP3A4 (0.51) | CACNA2D1CACNB1CACNA1ACACNA1CALDH1A1 | |
| SCHEMBL14459927 | 0.73 | CACNA2D1 (0.46) | CACNA2D1CACNB1CACNA1ACACNA1COPRD1 | |
| SCHEMBL4473810 | 0.72 | CCR5 (0.58) | CACNA2D1CACNB1CACNA1ACACNA1CALDH1A1 | |
| SCHEMBL4460130 | 0.72 | CCR5 (0.58) | CACNA2D1CACNB1CACNA1ACACNA1CALDH1A1 | |
| SCHEMBL4460125 | 0.72 | CCR5 (0.58) | CACNA2D1CACNB1CACNA1ACACNA1CALDH1A1 | |
| SCHEMBL14459926 | 0.72 | DPP4 (0.48) | OPRD1ALDH1A1L3MBTL1SLC6A9OPRM1 | |
| SCHEMBL13596969 | 0.70 | DPP4 (0.55) | OPRD1ALDH1A1GAAMAPTHTT | |
| SCHEMBL21075233 | 0.70 | DPP4 (0.55) | OPRD1ALDH1A1GAAMAPTHTT | |
| SCHEMBL5634347 | 0.70 | CACNA2D1 (0.54) | CACNA2D1CACNB1CACNA1ACACNA1COPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244758-B2 | N-type calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-07-17 | — | — | US | claimed |
| US-20050014748-A1 | N-type calcium channel blockers | NEUROMED TECHNOLOGIES INC. | 2005-01-20 | — | — | US | claimed |
| US-7244758-B2 | N-type calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014748-A1 | N-type calcium channel blockers | CACNA1B, CACNA1C, CACNA1I | CACNA2D1 30/4885CACNB1 13/4885CACNA1A 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.