Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852381 | 0.80 | NOTUM (0.45) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL5226699 | 0.80 | MEN1 (0.45) | MAPTGAATP53ALDH1A1MEN1 | |
| SCHEMBL10746811 | 0.77 | MEN1 (0.44) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7785220 | 0.76 | ALDH1A1 (0.44) | MAPTGAATP53ALDH1A1MEN1 | |
| SCHEMBL7126729 | 0.75 | ALDH1A1 (0.51) | MAPTGAATP53ALDH1A1MEN1 | |
| SCHEMBL29985725 | 0.75 | ALDH1A1 (0.51) | MAPTGAATP53ALDH1A1MEN1 | |
| SCHEMBL31311097 | 0.72 | PARL (0.43) | HTR7ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL395744 | 0.71 | MEN1 (0.77) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL5120536 | 0.71 | NOTUM (0.50) | MAPTGAATP53ALDH1A1MEN1 | |
| SCHEMBL29682974 | 0.71 | MEN1 (0.77) | MAPTGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117075-A1 | USE OF INDOLIN-PHENYLSULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2006-11-09 | — | — | WO | disclosed |
| WO-2006117076-A1 | USE OF INDOLIN-PHENYLSULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2006-11-09 | — | — | WO | disclosed |
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| CN-1678581-A | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-05 | — | — | CN | disclosed |
| CN-1678581-A | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-05 | — | — | CN | disclosed |
| CN-1678581-A | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-05 | — | — | CN | disclosed |
| EP-1519919-A1 | INDOLIN PHENYLSULFONAMIDE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005253-A1 | INDOLIN PHENYLSULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | PPARD, PPARA, PPARG | MAPT 4156/4885GAA 2558/4885TP53 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.