Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635476 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5635478 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL22118368 | 0.72 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTCXCR2 | |
| SCHEMBL5635129 | 0.70 | DRD2 (0.48) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL5634694 | 0.70 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5634697 | 0.70 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL4640324 | 0.68 | POLB (0.52) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22118419 | 0.67 | HTR2A (0.60) | ALDH1A1CXCR2DRD2HTR2AHTR2C | |
| SCHEMBL31006391 | 0.67 | HTR2A (0.60) | ALDH1A1CXCR2DRD2HTR2AHTR2C | |
| SCHEMBL7579500 | 0.66 | DRD2 (0.45) | KMT2AHPGDPTGS2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | US | claimed |
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | GPR119, IDO2, IDO1 | MEN1 4192/4885KMT2A 1438/4885ALDH1A1 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.