Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809770 | 0.74 | NR4A2 (0.49) | IDO1PTPN1NR4A2HSD17B10HPGD | |
| SCHEMBL27602913 | 0.73 | CXCR2 (0.44) | KMT2A | |
| SCHEMBL6995871 | 0.71 | TUBB4A (0.53) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9186814 | 0.70 | MMP2 (0.55) | HPGDKMT2AKDM4ERAB9A | |
| SCHEMBL28974916 | 0.69 | TUBB4A (0.57) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5635129 | 0.69 | DRD2 (0.48) | DRD2HTR2AHTR2CIDO1TDO2 | |
| SCHEMBL31006391 | 0.68 | HTR2A (0.60) | DRD2HTR2AHTR2CPPARGKDM4E | |
| SCHEMBL22118368 | 0.68 | MEN1 (0.49) | DRD2HTR2AHTR2CTDO2KMT2A | |
| SCHEMBL22118419 | 0.68 | HTR2A (0.60) | DRD2HTR2AHTR2CPPARGKDM4E | |
| SCHEMBL18671102 | 0.68 | MGLL (0.54) | KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222167-A2 | METHOD FOR PRODUCING INDOLE DERIVATIVES ON A SOLID PHASE | MERCK PATENT GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001023353-A2 | METHOD FOR PRODUCING INDOLE DERIVATIVES ON A SOLID PHASE | MERCK PATENT GMBH (DE) | 2001-04-05 | — | — | WO | disclosed |