Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PRKACA | P17612 | 4/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.52 |
| ▸ | PRKACG | P22612 | 3/20 | 0.52 |
| ▸ | PRKACB | P22694 | 3/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.52 |
| ▸ | PRKCG | P05129 | 2/20 | 0.52 |
| ▸ | PRKCB | P05771 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 2/20 | 0.52 |
| ▸ | PRKCH | P24723 | 2/20 | 0.52 |
| ▸ | PRKCI | P41743 | 2/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714375 | 1.00 | L3MBTL1 (0.58) | L3MBTL1KMT2APRKACAPRKD3PRKACG | |
| SCHEMBL16442259 | 1.00 | L3MBTL1 (0.58) | L3MBTL1KMT2APRKACAPRKD3PRKACG | |
| SCHEMBL3718844 | 0.85 | PSEN1 (0.61) | KMT2APRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL7892632 | 0.85 | PSEN1 (0.61) | KMT2APRKACAPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL1429753 | 0.84 | PSEN1 (0.59) | KMT2APRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL7895826 | 0.83 | PRKACA (0.52) | KMT2APRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL4563889 | 0.83 | PRKACA (0.49) | KMT2APRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL28092047 | 0.83 | AKR1C3 (0.58) | L3MBTL1KMT2APRKACAPRKD3PRKACG | |
| SCHEMBL10042202 | 0.82 | MMP1 (0.65) | L3MBTL1SMN1; SMN2TSHRRAB9AHTT | |
| SCHEMBL22501842 | 0.82 | TRPV4 (0.54) | L3MBTL1KMT2ASMN1; SMN2MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-101941953-B | Nitrogenous heterocyclic substituted hydrazide compounds as well as preparation methods and applications thereof | SHENZHEN XIANGYA BIOPHARMACEUTICAL INST | 2013-04-10 | — | — | CN | disclosed |
| US-8404690-B2 | Piperazine-2-carboxamide derivatives | MERCK SERONO SA (CH) | 2013-03-26 | — | — | US | disclosed |
| CN-101941953-A | Nitrogenous heterocyclic substituted hydrazide compounds as well as preparation methods and applications thereof | SHENZHEN XIANGYA BIOPHARMACEUTICAL INST | 2011-01-12 | — | — | CN | disclosed |
| US-20070142391-A1 | Piperazine-2-carboxamide derivatives | MERCK SERONO SA (CH) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142391-A1 | Piperazine-2-carboxamide derivatives | P2RX5, P2RX2, NPY5R | L3MBTL1 4633/4885KMT2A 396/4885PRKACA 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.