SCHEMBL5635779

SCHEMBL5635779

Oc1ccccc1NC=S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.47
HTT P42858 4/20 0.47
MAPT P10636 6/20 0.43
RAB9A P51151 6/20 0.43
NPC1 O15118 5/20 0.43
KDM4E B2RXH2 4/20 0.43
LMNA P02545 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MMP9 P14780 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
CA12 O43570 2/20 0.43
CA2 P00918 2/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
FYN P06241 1/20 0.43
POLB P06746 1/20 0.43
CA3 P07451 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764228 0.84 ALDH1A1 (0.35) GAAHTTMAPTRAB9ANPC1
SCHEMBL29876843 0.78 GAA (0.50) GAAHTTMAPTRAB9ANPC1
SCHEMBL1939410 0.78 GAA (0.50) GAAHTTMAPTRAB9ANPC1
SCHEMBL14411538 0.78 GAA (0.46) GAAHTTMAPTRAB9ANPC1
SCHEMBL22663499 0.78 TRPA1 (0.46) GAAHTTMAPTRAB9ANPC1
SCHEMBL1943622 0.74
SCHEMBL1268881 0.73 ALDH1A1 (0.47) HTTMAPTRAB9AKDM4ELMNA
SCHEMBL3166136 0.73 SMN1; SMN2 (0.45) GAAHTTMAPTRAB9ANPC1
SCHEMBL6304709 0.73 SIGMAR1 (0.36)
SCHEMBL11289154 0.73 MAPT (0.48) GAAHTTMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229450-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2006-10-12 US claimed
US-7084272-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2006-08-01 US claimed
US-20040242607-A1 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2004-12-02 US claimed
EP-1399427-B1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LTD (GB) 2004-11-03 EP claimed
EP-1399427-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF Syngenta Limited (GB) 2004-03-24 EP claimed
WO-2002100837-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2002-12-19 WO claimed
US-7244737-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2007-07-17 US disclosed
US-7244737-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2007-07-17 US disclosed
US-20060229450-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2006-10-12 US disclosed
US-20060229450-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2006-10-12 US disclosed
US-7084272-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2006-08-01 US disclosed
US-7084272-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2006-08-01 US disclosed
CN-1259313-C Process for preparation of azoxystrobin and analogues thereof SYNGENTA LTD (GB) 2006-06-14 CN disclosed
EP-1399427-B1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LTD (GB) 2004-11-03 EP disclosed
EP-1399427-B1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LTD (GB) 2004-11-03 EP disclosed
CN-1511144-A Process for preparation of azoxystrobin and analogues thereof 2004-07-07 CN disclosed
EP-1399427-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF Syngenta Limited (GB) 2004-03-24 EP disclosed
EP-1399427-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF Syngenta Limited (GB) 2004-03-24 EP disclosed
WO-2002100837-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2002-12-19 WO disclosed
WO-2002100837-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242607-A1 Process for the preparation of azoxystrobin and analogues thereof CYP4F2, PAH, FBL GAA 1862/4885HTT 1681/4885MAPT 4786/4885
US-20060229450-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF CYP4F2, CYP4F11, CYP4B1 GAA 1224/4885HTT 2722/4885MAPT 4805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.