SCHEMBL8764228

SCHEMBL8764228

S=CNc1ccccc1NC=S

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
POLB P06746 2/20 0.35
HPGD P15428 2/20 0.35
RECQL P46063 2/20 0.35
HSD17B10 Q99714 2/20 0.35
USP2 O75604 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 2/20 0.31
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.31
CA12 O43570 3/20 0.31
CA2 P00918 3/20 0.31
CA9 Q16790 2/20 0.31
CA5A P35218 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5635779 0.84 GAA (0.47) ALDH1A1KDM4EMAPTTDP1L3MBTL1
SCHEMBL1268881 0.82 ALDH1A1 (0.47) ALDH1A1KDM4EMAPTHPGDRECQL
SCHEMBL11289154 0.82 MAPT (0.48) ALDH1A1KDM4EMAPTTDP1L3MBTL1
SCHEMBL3166136 0.82 SMN1; SMN2 (0.45) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL6304709 0.82 SIGMAR1 (0.36)
SCHEMBL8763185 0.80 HSPA5 (0.41) ALDH1A1KDM4EMAPTTDP1L3MBTL1
SCHEMBL11915496 0.78 ALDH1A1 (0.44) ALDH1A1MAPTL3MBTL1HPGDHSD17B10
SCHEMBL2102036 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTTDP1HPGD
SCHEMBL4739130 0.77 L3MBTL1 (0.48) MAPTL3MBTL1POLBHPGDRECQL
SCHEMBL3847160 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed