Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562499 | 0.87 | MAPT (0.40) | ALDH1A1CYP2D6ATMPTGS2NPSR1 | |
| SCHEMBL563260 | 0.80 | TLR7 (0.42) | ALDH1A1PTGS2SLC2A1TLR7TLR8 | |
| SCHEMBL562853 | 0.72 | EGFR (0.46) | ALDH1A1NPSR1TLR7TLR8CA1 | |
| SCHEMBL28585742 | 0.69 | ALDH1A1 (0.64) | ALDH1A1CYP2D6ATMNPSR1SMN1; SMN2 | |
| SCHEMBL23612255 | 0.67 | ALDH1A1 (0.82) | ALDH1A1CYP2D6ATMNPSR1SMN1; SMN2 | |
| SCHEMBL30055740 | 0.67 | ALDH1A1 (0.82) | ALDH1A1CYP2D6ATMNPSR1SMN1; SMN2 | |
| SCHEMBL30547170 | 0.67 | ATM (0.51) | ALDH1A1CYP2D6ATMNPSR1MAPT | |
| SCHEMBL29090412 | 0.67 | ATM (0.51) | ALDH1A1CYP2D6ATMNPSR1MAPT | |
| SCHEMBL28528829 | 0.66 | ALDH1A1 (0.69) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL854178 | 0.65 | ALDH1A1 (0.51) | ALDH1A1CYP2D6ATMNPSR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035209-A1 | Hydroxy Substituted 1H-Imidazopyridines and Methods | PFIZER INC. (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035209-A1 | Hydroxy Substituted 1H-Imidazopyridines and Methods | IL2, IL4, IL4I1 | ALDH1A1 623/4885CYP2D6 660/4885ATM 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.