Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | HEXA | P06865 | 1/20 | 0.54 |
| ▸ | HEXB | P07686 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391873 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL23612255 | 0.86 | ALDH1A1 (0.82) | ALDH1A1CYP2D6ATMHEXAHEXB | |
| SCHEMBL30055740 | 0.86 | ALDH1A1 (0.82) | ALDH1A1CYP2D6ATMHEXAHEXB | |
| SCHEMBL28585742 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL29937212 | 0.78 | NPSR1 (0.72) | ALDH1A1CYP2D6ATMHEXAHEXB | |
| SCHEMBL28052342 | 0.78 | DHFR (0.51) | ALDH1A1CYP2D6ATMHEXAHEXB | |
| SCHEMBL16943987 | 0.78 | MPO (0.53) | CYP2D6HEXAHEXBDHFR | |
| SCHEMBL29558689 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL23175129 | 0.76 | LMNA (0.70) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL2325153 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP2D6ATMHEXAHEXB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427063-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |
| CN-112533607-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2021-03-19 | — | — | CN | disclosed |