Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MVD | P53602 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361217 | 0.82 | GMNN (0.60) | MAPTTHRBGMNNTP53POLB | |
| SCHEMBL7434559 | 0.81 | ALDH1A1 (0.39) | MAPTTHRBGMNNTP53POLB | |
| SCHEMBL17418181 | 0.81 | LMNA (0.58) | MAPTHSD17B10ALDH1A1TSHRBHMT | |
| SCHEMBL27562447 | 0.80 | CYP2D6 (0.48) | MAPTTHRBGMNNTP53POLB | |
| SCHEMBL9640732 | 0.79 | MVD (0.47) | MAPTTHRBGMNNTP53POLB | |
| Hydrochloric Acid SCHEMBL11155644 | 0.78 | CYP2D6 (0.46) | MAPTTHRBGMNNTP53POLB | |
| SCHEMBL5994074 | 0.78 | CYP2D6 (0.46) | MAPTTHRBGMNNTP53POLB | |
| SCHEMBL5639474 | 0.77 | — | — | |
| SCHEMBL7546724 | 0.75 | ALDH1A1 (0.45) | THRBALDH1A1TSHR | |
| SCHEMBL16710671 | 0.75 | ALDH1A1 (0.54) | MAPTPOLBHIF1AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993307-A2 | TECHNETIUM-99m LABELED CHELATOR INCORPORATED CYCLIC PEPTIDES | Du Pont Pharmaceuticals Company (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0813425-A4 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORP (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5756685-A | MEDICAL DIAGNOSIS; THERAPY | NEORX CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1998014220-A2 | TECHNETIUM-99m LABELED CHELATOR INCORPORATED CYCLIC PEPTIDES | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-04-09 | — | — | WO | disclosed |
| EP-0813425-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0510132-B1 | POLYMERIC CARRIERS FOR RELEASE OF COVALENTLY LINKED AGENTS | NEORX CORP (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5625075-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5556982-A | Metal radionuclide labeled proteins for diagnosis and therapy | NEORX CORPORATION (US) | 1996-09-17 | — | — | US | disclosed |
| US-5549883-A | (OLIGO OR POLY)PEPTIDES | NEORX CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| US-5436352-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1995002423-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| EP-0461245-A4 | RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE | GUSTAVSON LINDA M (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0344724-B1 | METAL RADIONUCLIDE CHELATING COMPOUNDS FOR IMPROVED CHELATION KINETICS | NEORX CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0510132-A4 | POLYMERIC CARRIERS FOR RELEASE OF COVALENTLY LINKED AGENTS | — | 1993-02-24 | — | — | EP | disclosed |
| EP-0510132-A1 | POLYMERIC CARRIERS FOR RELEASE OF COVALENTLY LINKED AGENTS. | NEORX CORP (US) | 1992-10-28 | — | — | EP | disclosed |
| WO-1992005802-A1 | POLYMERIC CARRIERS FOR RELEASE OF COVALENTLY LINKED AGENTS | NEORX CORPORATION (US) | 1992-04-16 | — | — | WO | disclosed |
| US-5075099-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-4988496-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0344724-A2 | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4279806-A | Antimony mercaptides as processing stabilizers for vinyl halide resins | ASSOCIATED LEAD INC. (US) | 1981-07-21 | — | — | US | disclosed |