SCHEMBL599657

SCHEMBL599657

Nc1ccc(-c2ccccc2N)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
HSD17B10 Q99714 3/20 0.71
L3MBTL1 Q9Y468 1/20 0.60
CYP3A4 P08684 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
TAAR1 Q96RJ0 1/20 0.55
BCHE P06276 1/20 0.53
ACHE P22303 1/20 0.53
TP53 P04637 2/20 0.50
NCOA1 Q15788 2/20 0.45
NCOA3 Q9Y6Q9 2/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
ALOX15 P16050 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
PRKCZ Q05513 1/20 0.44
DHFR P00374 1/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510158 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL31264297 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL7141191 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Methane SCHEMBL3050883 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL29471400 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Hydrogen Sulfide SCHEMBL34563 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Hydrogen Sulfide SCHEMBL3678041 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Water SCHEMBL2446952 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Biphenyl-4-Amine SCHEMBL6081432 0.93 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Benzidine SCHEMBL28123514 0.93 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 576 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
CN-120092033-A Novel polyurethane or polyurethane-urea compositions with enhanced low temperature properties 英格维蒂英国有限公司 2025-06-03 CN claimed
CN-117887124-B PTFE/modified polyimide composite film with high-temperature bonding performance and preparation method and application thereof 无锡顺铉新材料有限公司 2025-03-04 CN claimed
CN-118725295-A Resin, preparation method and application of resin 华为技术有限公司 2024-10-01 CN claimed
CN-115739042-B Surface-modified magnetic nanoparticle and method for separating multivalent phage in water 浙江大学 2024-06-04 CN claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US claimed
JP-2007504305-A 2007-03-01 JP claimed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US claimed
US-20050103258-A1 Epitaxial organic layered structure and method for making INSOLVENCY SERVICES GROUP, INC. 2005-05-19 US claimed
WO-2005032217-A1 EPITAXIAL ORGANIC LAYERED STRUCTURE AND METHOD FOR MAKING NITTO DENKO CORPORATION (JP) 2005-04-07 WO claimed
WO-2004065524-A1 ANISOTROPIC FILM MANUFACTURING NITTO DENKO CORPORATION (JP) 2004-08-05 WO claimed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US claimed
EP-0785578-A2 Circuit comprising complementary thin film transistors AT&T Corp. (US) 1997-07-23 EP claimed
US-5625199-A Article comprising complementary circuit with inorganic n-channel and organic p-channel thin film transistors LUCENT TECHNOLOGIES INC. (US) 1997-04-29 US claimed
US-4095948-A ABENZIDINE OR DIPHENYLINE AND PEROXIDASE AS COLOR INDICATOR HOFFMANN-LA ROCHE INC. (US) 1978-06-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS PUF60, MORF4L1, C9 ALDH1A1 538/4885HSD17B10 223/4885L3MBTL1 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.