Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.62 |
| ▸ | FAAH | O00519 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373792 | 0.82 | MGLL (0.76) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL145737 | 0.82 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14678413 | 0.82 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL29064617 | 0.80 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL1495341 | 0.80 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL6723806 | 0.80 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL564245 | 0.77 | — | — | |
| SCHEMBL155748 | 0.77 | MGLL (1.00) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL331378 | 0.77 | MGLL (0.88) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL20351983 | 0.74 | MGLL (1.00) | MGLLFAAHALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112646220-B | Atomic oxygen prevention polyimide composite film and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-08-31 | — | — | CN | claimed |
| CN-113144214-A | Synthesis and application of novel antibody drug targeting CD45 and constructed through chemical coupling | 乾元康安(苏州)生物科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-112646187-A | Self-crosslinking trapezoidal polysilsesquioxane polymer and preparation method and application thereof | 中国科学院上海硅酸盐研究所 | 2021-04-13 | — | — | CN | claimed |
| CN-112646220-A | Atomic oxygen prevention polyimide composite film and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-04-13 | — | — | CN | claimed |
| US-20210077571-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-3773740-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | Heidelberg Pharma Research GmbH (DE) | 2021-02-17 | — | — | EP | claimed |
| CN-111989122-A | Targeted amatoxin conjugates for the treatment of solid tumors | 海德堡医药研究有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| WO-2019197654-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2019-10-17 | — | — | WO | claimed |
| CN-108329371-A | Albumin combination type gemcitabine prodrug and its synthesis and application | 沈阳药科大学 | 2018-07-27 | — | — | CN | claimed |
| CN-107050468-A | The preparation method of conjugate | 伊缪诺金公司 | 2017-08-18 | — | — | CN | claimed |
| CN-102569886-B | Non-aqueous electrolyte and lithium secondary battery comprising the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (CN) | 2015-08-05 | — | — | CN | claimed |
| JP-2005517708-A | — | — | 2005-06-16 | — | — | JP | claimed |
| US-20040116702-A1 | Alkoxylated acyl-and bisacylphoshine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-17 | — | — | US | claimed |
| WO-2003068783-A1 | ALKOXYLATED ACYL- AND BISACYLPHOSPHINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | WO | claimed |
| EP-0850920-B1 | Ionic conductive materials comprising salts of perfluorinated amides and uses thereof | CENTRE NAT RECH SCIENT (FR) | 2002-09-11 | — | — | EP | claimed |
| US-6165672-A | Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2000-12-26 | — | — | US | claimed |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | SEAGEN INC. | 2024-07-11 | — | — | US | disclosed |
| CN-1119415-A | Substance for detecting amyloid deposits | KANEGAFUCHI CHEMICAL IND (JP) | 1996-03-27 | — | — | CN | disclosed |
| US-5360895-A | Derivatized gold clusters and antibody-gold cluster conjugates | ASSOCIATED UNIVERSITIES, INC. (US) | 1994-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | EPCAM, TOP2A, SPAG5 | MGLL 4028/4885FAAH 3433/4885ALDH1A1 388/4885 |
| US-20210077571-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | C3AR1, ANTXR2, C5AR2 | MGLL 4690/4885FAAH 2568/4885ALDH1A1 4043/4885 |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | CTSB, CTSE, CTSZ | MGLL 1865/4885FAAH 669/4885ALDH1A1 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.