Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | STAT3 | P40763 | 2/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 8/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574220 | 0.86 | ALDH1A1 (0.63) | ALOX5STAT3NFE2L2NFKB1NFKB2 | |
| SCHEMBL1001955 | 0.86 | ALDH1A1 (0.63) | ALOX5STAT3NFE2L2NFKB1NFKB2 | |
| Syringaldehyde SCHEMBL150376 | 0.86 | ALDH1A1 (0.62) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL2110596 | 0.86 | ALDH1A1 (0.62) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL30119623 | 0.86 | ALDH1A1 (0.62) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL28642631 | 0.84 | ALDH1A1 (0.60) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL11013780 | 0.84 | ALDH1A1 (0.60) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL28299840 | 0.84 | ALDH1A1 (0.60) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL29724072 | 0.84 | ALDH1A1 (0.60) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL27352107 | 0.84 | ALDH1A1 (0.60) | PTGS1ALDH1A1TRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| EP-3953342-B1 | IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME | UNIV MIAMI (US) | 2025-09-24 | — | — | EP | disclosed |
| US-RE50453-E1 | Indole derivatives as CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| US-12275725-B2 | Inhibitors of the notch transcriptional activation complex and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2025-04-15 | — | — | US | disclosed |
| CN-119390668-A | Compound with ketoxime ether structure and application thereof | 复旦大学 | 2025-02-07 | — | — | CN | disclosed |
| US-20250011285-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2025-01-09 | — | — | US | disclosed |
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | SPRING MILL PHARMA, INC. | 2024-08-15 | — | — | US | disclosed |
| EP-4347607-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2024-03-21 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0400805-A1 | Cephalosporin compounds and their use | Ishimaru, Toshiyasu (JP) | 1990-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011285-A1 | CYP11A1 INHIBITORS | CYP11B1, CYP19A1, CYP11B2 | ALOX5 487/4885STAT3 2877/4885NFE2L2 585/4885 |
| US-12275725-B2 | Inhibitors of the notch transcriptional activation complex and methods for use of the same | NOTCH1, CBFB, HES1 | ALOX5 2293/4885STAT3 55/4885NFE2L2 141/4885 |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALOX5 3605/4885STAT3 3618/4885NFE2L2 1086/4885 |
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | ALOX5 4756/4885STAT3 4299/4885NFE2L2 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.