Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003665 | 0.88 | KMT2A (0.83) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL30131238 | 0.85 | MMP13 (0.58) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL5644060 | 0.84 | ALDH1A1 (0.55) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL30131237 | 0.84 | NSD2 (0.68) | HDAC1HDAC6KMT2AALDH1A1HTT | |
| SCHEMBL5645455 | 0.83 | NSD2 (0.67) | HDAC1HDAC6KMT2AMEN1MLYCD | |
| SCHEMBL5644480 | 0.83 | KMT2A (0.79) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL1196545 | 0.82 | KMT2A (0.60) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL15676750 | 0.82 | KMT2A (0.64) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL30131240 | 0.82 | NPC1 (0.61) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL7326042 | 0.81 | KMT2A (0.63) | HDAC1HDAC6KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112125817-B | Synthesis method of tertiary amide compound | 西北师范大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |