Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5641630 | 0.90 | CTH (0.38) | CTHDDAH1PTGER3 | |
| SCHEMBL5641866 | 0.86 | CTH (0.33) | CTHDDAH1 | |
| SCHEMBL5642486 | 0.82 | CTH (0.35) | CTHDDAH1 | |
| SCHEMBL5644037 | 0.80 | DDAH1 (0.33) | CTHDDAH1 | |
| SCHEMBL5642661 | 0.77 | DDAH1 (0.34) | CTHDDAH1 | |
| SCHEMBL5644452 | 0.74 | — | — | |
| SCHEMBL5644169 | 0.74 | CTH (0.39) | CTHDDAH1 | |
| SCHEMBL5642370 | 0.73 | CTH (0.36) | CTHDDAH1 | |
| SCHEMBL5643601 | 0.73 | CDK1 (0.31) | — | |
| SCHEMBL19859659 | 0.73 | CTH (0.41) | CTHDDAH1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250433-B2 | Tetrazole and oxadiazolone substituted β-amino acid derivatives | WARNER LAMBERT COMPANY LLC (US) | 2007-07-31 | — | — | US | disclosed |
| US-20050014804-A1 | Tetrazole and oxadiazolone substituted beta-amino acid derivatives | BARTA NANCY SUE (US) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014804-A1 | Tetrazole and oxadiazolone substituted beta-amino acid derivatives | GLRA2, CACNG5, GLRB | CTH 2144/4885DDAH1 1460/4885PTGER3 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.