Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648042 | 0.93 | NPC1 (0.34) | POLBRAB9ANPC1LMNA | |
| SCHEMBL5648161 | 0.93 | NPC1 (0.33) | POLBRAB9ANPC1LMNA | |
| SCHEMBL5647615 | 0.93 | NPC1 (0.33) | POLBRAB9ANPC1LMNA | |
| SCHEMBL4822434 | 0.89 | MEN1 (0.34) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL5646334 | 0.88 | GLO1 (0.31) | RAB9ANPC1 | |
| SCHEMBL5643755 | 0.88 | CNR2 (0.38) | KDRACSS2RAB9ANPC1MGLL | |
| SCHEMBL5645945 | 0.86 | ACSS2 (0.34) | POLBACSS2KDM4EALDH1A1HPGD | |
| SCHEMBL6613899 | 0.86 | NPC1 (0.32) | RAB9ANPC1 | |
| SCHEMBL5645121 | 0.85 | RXRA (0.31) | RAB9ANPC1 | |
| SCHEMBL5646861 | 0.85 | S1PR5 (0.35) | HTTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166659-B2 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-7148274-B2 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1337520-B1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| US-20040192927-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | PASTOR STEPHEN D (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040157966-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | PASTOR STEPHEN D (US) | 2004-08-12 | — | — | US | disclosed |
| US-6774238-B2 | REACTING 5-SUBSTITUTED BENZOTRIAZOLE WITH ARYLBORONIC ACID IN PRESENCE OF PALLADIUM CATALYST; DEHALOGENATION; ARYLATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-08-10 | — | — | US | disclosed |
| US-20040092628-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparatiion thereof | PASTOR STEPHEN D (US) | 2004-05-13 | — | — | US | disclosed |
| US-6703510-B2 | MORE STABLE AND DURABLE; AUTOMOTIVE COATINGS, CANDLE WAX | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-03-09 | — | — | US | disclosed |
| US-20030213164-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | PASTOR STEPHEN D (US) | 2003-11-20 | — | — | US | disclosed |
| US-6649770-B1 | Exhibit superior hydrolytic stability, handling and storage stability as well as good resistance to extractability when present in stabilized composition | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-18 | — | — | US | disclosed |
| EP-1337520-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | Ciba SC Holding AG (CH) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002042281-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192927-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | EBPL, DDT, AHR | KDR 1487/4885HTT 907/4885POLB 531/4885 |
| US-20030213164-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | EBPL, DDT, AHR | KDR 1487/4885HTT 907/4885POLB 531/4885 |
| US-20040092628-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparatiion thereof | AHR, PAH, CCNL2 | KDR 2778/4885HTT 1322/4885POLB 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.