SCHEMBL5645355

SCHEMBL5645355

Oc1ccc[c]c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135028 0.72
SCHEMBL59224 0.72
SCHEMBL5584043 0.72 LMNA (0.31)
SCHEMBL16952915 0.69
SCHEMBL10534196 0.68
SCHEMBL314757 0.68
SCHEMBL458734 0.68
SCHEMBL128265 0.68
SCHEMBL1179676 0.68
SCHEMBL1028751 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166592-B2 Antiinflammatory agents SCHERING AKTIENGESELLSCHAFT (DE) 2007-01-23 US claimed
EP-0624166-B1 POLYMERIZABLE CARBOHYDRATE ESTERS, POLYMERS MADE FROM SUCH ESTERS AND THE USE OF SUCH POLYMERS CIBA GEIGY AG (CH) 1997-04-16 EP claimed
US-5571882-A CONTACT LENSES CIBA-GEIBY CORPORATION (US) 1996-11-05 US claimed
EP-0624166-A1 POLYMERIZABLE CARBOHYDRATE ESTERS, POLYMERS MADE FROM SUCH ESTERS AND THE USE OF SUCH POLYMERS. CIBA GEIGY AG (CH) 1994-11-17 EP claimed
WO-1994012540-A1 POLYMERIZABLE CARBOHYDRATE ESTERS, POLYMERS MADE FROM SUCH ESTERS AND THE USE OF SUCH POLYMERS CIBA-GEIGY AG (CH) 1994-06-09 WO claimed
EP-0566533-A1 Sulfated vinylphenol polymers, compositions containing sulfated vinylphenol polymers and the use thereof CIBA-GEIGY AG (CH) 1993-10-20 EP claimed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US claimed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP claimed
US-4138265-A Antifoggants in certain photographic and photothermographic materials that include silver salts of 3-amino-1,2,4-mercaptotriazole EASTMAN KODAK COMPANY (US) 1979-02-06 US claimed
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN disclosed
CN-107428690-B Mutant IDH1 inhibitors useful for the treatment of cancer 美国政府健康及人类服务部 2021-04-13 CN disclosed
WO-2021006267-A1 SALT OF PYRAZOLE DERIVATIVE AND PREPARATION OF PYRAZOLE DERIVATIVE グリーン・テック株式会社 2021-01-14 WO disclosed
WO-2020235582-A1 PREVENTIVE AND/OR THERAPEUTIC AGENT FOR MOTOR NEURON DISEASE グリーン・テック株式会社 (JP) 2020-11-26 WO disclosed
CN-109232468-B Camphorsulfonic thiosemicarbazone thiazole compound, and preparation method and application thereof 南京林业大学 2020-05-19 CN disclosed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US disclosed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP disclosed
US-4831027-A USEFUL IN TREATMENT OF CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1989-05-16 US disclosed
US-4361563-A CARDIOTONIC, ANTITHROMBOTIC DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-11-30 US disclosed
US-4176184-A CARDIOTONICS, HYPOTENSIVES, ANTITHROMBOTICS AND ANTIARRHYTHMICS BOEHRINGER INGELHEIM GMBH (DE) 1979-11-27 US disclosed
US-4138265-A Antifoggants in certain photographic and photothermographic materials that include silver salts of 3-amino-1,2,4-mercaptotriazole EASTMAN KODAK COMPANY (US) 1979-02-06 US disclosed