Sugi Predict

Sugi Predict / Compounds / SCHEMBL564668

SCHEMBL564668

SCHEMBL564668

Cc1c(F)c(O)cc(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SELL P14151 1/20 0.38
▸ SELP P16109 1/20 0.38
▸ SELE P16581 1/20 0.38
▸ ACHE P22303 1/20 0.38
▸ CA3 P07451 1/20 0.33
▸ CA6 P23280 1/20 0.33
▸ CA5A P35218 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ CA5B Q9Y2D0 1/20 0.33
▸ CES2 O00748 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ HSD17B3 P37058 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ GAA P10253 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ MPI P34949 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27804340 0.97 SELL (0.36) SELLSELPSELEACHECA3
SCHEMBL3687919 0.84 SELL (0.43) SELLSELPSELEACHECA3
Methyl Alcohol SCHEMBL9652269 0.80 CA1 (0.40) SELLSELPSELEACHECES2
SCHEMBL169896 0.80 CA1 (0.38) ACHECES2CES1HDAC1HDAC6
SCHEMBL3047779 0.79 SELL (0.38) SELLSELPSELEACHECA3
SCHEMBL374990 0.79 ACHE (0.43) SELLSELPSELEACHECA3
SCHEMBL30413280 0.79 ACHE (0.43) SELLSELPSELEACHECA3
SCHEMBL27565914 0.77 SELL (0.36) SELLSELPSELEACHECA3
SCHEMBL258682 0.75 CES2 (0.38) SELLSELPSELECA3CA6
SCHEMBL29716720 0.75 CES2 (0.38) SELLSELPSELECA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105153144-B Main chain diamine type quinoxalinyl benzoxazine and preparation method thereof 哈尔滨工程大学 2017-11-28 — — CN claimed
CN-103304558-B Containing benzoyloxy spiral shell fluorenes oxa-anthryl benzoxazine and preparation method HARBIN ENGINEERING UNIV. (CN) 2016-01-27 — — CN claimed
CN-105153144-A Main-chain diamine type quinoxalinyl benzoxazine and preparation method thereof UNIV HARBIN ENG 2015-12-16 — — CN claimed
CN-104271219-A Regenerable solvent mixtures for acid gas separation RES TRIANGLE INST 2015-01-07 — — CN claimed
CN-103304558-A Spirofluorene xanthene benzoxazine containing benzoyloxy group and preparation method thereof UNIV HARBIN ENG 2013-09-18 — — CN claimed
CN-102924512-A Preparation method of [2-oxo-3-(2-(trifluoromethyl phenoxyl)propyl)]dimethyl phosphate and isomer thereof SHANGHAI RAINBOW CHEMICAL CO LTD 2013-02-13 — — CN claimed
CN-101709052-A Preparation method of 2-(3-trifluoromethyl phenoxy) niacin NANJING FIRST AGRICULTURAL CHE 2010-05-19 — — CN claimed
CN-1962713-B Fluorine-containing phenol resin derivative and its composition and preparation method CHINESE ACAD INST CHEMISTRY 2010-05-05 — — CN claimed
CN-101490103-A Catalyst activators, methods of making, and uses thereof in catalysts and olefin polymerization ALBEMARLE CORP (US) 2009-07-22 — — CN claimed
CN-1962713-A Fluorine-containing phenol resin derivative and its composition and preparation method CHINESE ACAD INST CHEMISTRY (CN) 2007-05-16 — — CN claimed
CN-1194952-C Green synthetic process for high efficiency low poison pesticide and medicinal intermediate trifluoromethylphenol SHANGDONG NORMAL UNIV (CN) 2005-03-30 — — CN claimed
CN-1161342-C Process for preparing substituted pyrimidines �����ɷ� 2004-08-11 — — CN claimed
CN-1425638-A Green synthetic process for high efficiency low poison pesticide and medicinal intermediate trifluoromethylphenol UNIV SHANDONG (CN) 2003-06-25 — — CN claimed
CN-1355792-A process for preparation of substituted pyrimidines BASF AG (DE) 2002-06-26 — — CN claimed
CN-1045267-A The polymerization process of huge norbornene derivative and the polymkeric substance that makes thus SHELL INT RESEARCH (NL) 1990-09-12 — — CN claimed
CN-1042920-A The copolyreaction of Dicyclopentadiene (DCPD) and norbornene derivative and gained multipolymer thereof SHELL INT RESEARCH (NL) 1990-06-13 — — CN claimed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 — — US disclosed
US-11180461-B2 Triazoles as Kv3 inhibitors AUTIFONY THERAPEUTICS LIMITED (GB) 2021-11-23 — — US disclosed
EP-0002590-B1 NOVEL PROSTAGLANDIN COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AMERICAN CYANAMID COMPANY (US) 1981-09-30 — — EP disclosed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11180461-B2 Triazoles as Kv3 inhibitors KCNA3, KCNN3, KCNK3 SELL 4614/4885SELP 4437/4885SELE 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.