SCHEMBL564746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL564678	0.91	ALDH1A1 (0.50)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL563872	0.88	ALDH1A1 (0.61)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL564969	0.86	CYP3A4 (0.59)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL564670	0.83	CYP3A4 (0.52)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL564967	0.82	MAPT (0.60)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL19152170	0.81	ALDH1A1 (0.42)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL12277454	0.80	PDE10A (0.61)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL563902	0.80	CYP3A4 (0.62)	ALDH1A1MAPTALOX12CYP3A4CYP1A2
	SCHEMBL11475061	0.78	CYP3A4 (0.70)	ALDH1A1MAPTALOX12CYP3A4HTT
	SCHEMBL17506795	0.77	MAPT (0.43)	ALDH1A1MAPTALOX12CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.