SCHEMBL5648979

SCHEMBL5648979

OC1CCN(CC2CCNCC2)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.50
CACNA2D1 P54289 1/20 0.42
CACNA1B Q00975 1/20 0.42
CACNB1 Q02641 1/20 0.42
CHRM5 P08912 1/20 0.40
ADRA2C P18825 1/20 0.40
ACHE P22303 3/20 0.39
GNAO1 P09471 3/20 0.38
AXL P30530 1/20 0.36
FLT3 P36888 1/20 0.36
TYRO3 Q06418 1/20 0.36
MERTK Q12866 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR4 Q13639 1/20 0.36
JAK2 O60674 1/20 0.35
JAK1 P23458 1/20 0.35
TYK2 P29597 1/20 0.35
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19063632 0.88 SLC6A1 (0.41) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL19063634 0.88 SLC6A1 (0.41) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL19063705 0.88 SLC6A1 (0.41) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL988572 0.84 CHRM5 (0.48) CHRM5ADRA2CACHESMN1; SMN2JAK2
SCHEMBL14422030 0.84 GBA1 (0.48) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL22907051 0.84 GBA1 (0.47) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL24838354 0.83 GBA1 (0.42) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL16303417 0.83 GBA1 (0.50) GBA1CACNA2D1CACNA1BCACNB1CHRM5
Hydrochloric Acid SCHEMBL5573130 0.82 GBA1 (0.47) GBA1CACNA2D1CACNA1BCACNB1CHRM5
SCHEMBL2570307 0.82 GBA1 (0.47) GBA1CACNA2D1CACNA1BCACNB1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122050-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
CN-113122050-B Quantum dot ink and preparation method of quantum dot film TCL科技集团股份有限公司 2022-11-04 CN disclosed
CN-113122050-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN disclosed
US-7279470-B2 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2007-10-09 US disclosed
US-7067517-B2 Use of compounds for decreasing activity of hormone-sensitive lipase NERO NORDISK A/S (DK) 2006-06-27 US disclosed
EP-1458374-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-09-22 EP disclosed
EP-1458375-A2 COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-09-22 EP disclosed
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003051842-A2 COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase LIPE, PNLIP, LPL GBA1 451/4885CACNA2D1 4655/4885CACNA1B 4639/4885
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive LIPE, PNLIP, LPL GBA1 474/4885CACNA2D1 4355/4885CACNA1B 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.