Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145833 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5650842 | 0.83 | NPY5R (0.45) | ALDH1A1TSHRRAB9ANPC1TP53 | |
| SCHEMBL3691553 | 0.76 | KDM1A (0.45) | ALDH1A1TSHRRAB9ANPC1KDM1A | |
| SCHEMBL5649594 | 0.75 | KDM4E (0.48) | ALDH1A1TSHRMAPTKDM1AMAOA | |
| SCHEMBL9381194 | 0.74 | CTSL (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13145817 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20492711 | 0.71 | CYP2D6 (0.67) | TSHRSIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL11999842 | 0.71 | LTA4H (0.52) | ALDH1A1TSHRMAPTSMN1; SMN2KDM1A | |
| SCHEMBL28743107 | 0.70 | CTSL (0.48) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17140257 | 0.70 | KEAP1 (0.51) | ALDH1A1RAB9ANPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | ALDH1A1 2434/4885TSHR 4639/4885RAB9A 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.