Sugi Predict

Sugi Predict / Compounds / SCHEMBL565071

SCHEMBL565071

SCHEMBL565071

C=CCNc1cccc(C(C)(C)c2ccc(O)c(NCC=C)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 2/20 0.39
▸ ESR2 Q92731 1/20 0.39
▸ KLF10 Q13118 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ GAA P10253 2/20 0.35
▸ RORC P51449 1/20 0.35
▸ MAPT P10636 2/20 0.33
▸ CNR1 P21554 2/20 0.33
▸ CNR2 P34972 2/20 0.33
▸ P2RX1 P51575 1/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ ALOX12 P18054 1/20 0.33
▸ BRD4 O60885 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566137 0.90 ESR1 (0.39) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565866 0.89 ESR1 (0.46) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565964 0.88 ESR1 (0.43) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565833 0.88 CA12 (0.41) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL564549 0.88 ALDH1A1 (0.45) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL566122 0.84 ESR1 (0.46) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565593 0.78 ESR1 (0.43) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565501 0.78 ESR1 (0.42) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL565156 0.77 CA12 (0.41) ESR1ESR2KLF10ALDH1A1KDM4E
SCHEMBL564566 0.77 ALDH1A1 (0.45) ESR1ESR2KLF10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ESR1 1065/4885ESR2 1253/4885KLF10 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.